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  2. Glucose clamp technique - Wikipedia

    en.wikipedia.org/wiki/Glucose_clamp_technique

    The glucose clamp technique was developed by University of Texas (UT) School of Medicine Professors DeFronzo, Andres and Tobin in 1979. [2] It has since been the gold standard for pharmacodynamic studies in diabetes drug development and diagnostics evaluation. [3] In human clinical trials, manual glucose clamps as well as the more modern method ...

  3. Diabetes management - Wikipedia

    en.wikipedia.org/wiki/Diabetes_management

    Diabetes management. The term diabetes includes several different metabolic disorders that all, if left untreated, result in abnormally high concentrations of a sugar called glucose in the blood. Diabetes mellitus type 1 results when the pancreas no longer produces significant amounts of the hormone insulin, usually owing to the autoimmune ...

  4. Milling (machining) - Wikipedia

    en.wikipedia.org/wiki/Milling_(machining)

    Milling is the process of machining using rotary cutters to remove material [ 1 ] by advancing a cutter into a workpiece. This may be done by varying directions [ 2 ] on one or several axes, cutter head speed, and pressure. [ 3 ] Milling covers a wide variety of different operations and machines, on scales from small individual parts to large ...

  5. Glucose tolerance test - Wikipedia

    en.wikipedia.org/wiki/Glucose_tolerance_test

    The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...

  6. Gastric bypass surgery - Wikipedia

    en.wikipedia.org/wiki/Gastric_bypass_surgery

    Gastric bypass is indicated for the surgical treatment of morbid obesity, a diagnosis which is made when the patient is seriously obese, has been unable to achieve satisfactory and sustained weight loss by dietary efforts, and has comorbid conditions which are either life-threatening or serious impairment to the quality of life.

  7. Insulin tolerance test - Wikipedia

    en.wikipedia.org/wiki/Insulin_tolerance_test

    Insulin tolerance test. An insulin tolerance test (ITT) is a medical diagnostic procedure during which insulin is injected into a patient's vein, after which blood glucose is measured at regular intervals. This procedure is performed to assess pituitary function, adrenal function, insulin sensitivity, [1][2] and sometimes for other purposes.

  8. Three Mile Island accident - Wikipedia

    en.wikipedia.org/wiki/Three_Mile_Island_accident

    TMI training and operating procedures left operators and management ill-prepared for the deteriorating situation caused by the LOCA. During the accident, those inadequacies were compounded by design flaws, such as poor control design, the use of multiple similar alarms, and a failure of the equipment to indicate either the coolant-inventory ...

  9. Pancreatic beta cell function - Wikipedia

    en.wikipedia.org/wiki/Pancreatic_beta_cell_function

    Pancreatic beta cell function (synonyms Gβ or, if calculated from fasting concentrations of insulin and glucose, HOMA-Beta or SPINA-GBeta) is one of the preconditions of euglycaemia, i.e. normal blood sugar regulation. It is defined as insulin secretory capacity, i.e. the maximum amount of insulin to be produced by beta cells in a given unit ...

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