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IgA vasculitis (HSP), previously known as Henoch–Schönlein purpura, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain .
Cryofibrinogenemia refers to a condition classified as a fibrinogen disorder in which a person's blood plasma is allowed to cool substantially (i.e. from its normal temperature of 37 °C to the near-freezing temperature of 4 °C), causing the (reversible) precipitation of a complex containing fibrinogen, fibrin, fibronectin, and, occasionally, small amounts of fibrin split products, albumin ...
Purpura is one of the main characteristics of Acute hemorrhagic edema of infancy. Specialty: Dermatology: Symptoms: Purpura, edema, and fever [1] Usual onset: 4 months and 2 years of age. [1] Duration: 1–3 weeks. [1] Differential diagnosis: Henoch-Schönlein purpura [1]
287 Purpura and other hemorrhagic conditions. 287.0 Allergic purpura Henoch–Schönlein purpura; 287.3 Thrombocytopenia, primary 287.31 Immune thrombocytopenic purpura. Idiopathic thrombocytopenic purpura; 287.4 Thrombocytopenia, secondary; 287.9 Hemorrhagic conditions, unspec.
In diseases such as hemolytic uremic syndrome, disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, and malignant hypertension, the endothelial layer of small vessels is damaged with resulting fibrin deposition and platelet aggregation. As red blood cells travel through these damaged vessels, they are fragmented ...
Henoch–Schönlein purpura (HSP) - Often considered a systemic form of IgA nephropathy, Henoch–Schönlein purpura (HSP) is a systemic small-vessel vasculitis that is characterized by deposition of IgA antibody immune complexes in different key areas throughout the body.
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In cases where a cause can be determined, medications and infectious pathogens are most common in adults, while IgA vasculitis (Henoch–Schönlein purpura) frequently affects children. [6] Other etiologies include autoimmune conditions and malignancies, usually hematologic (related to the blood). [5] [6]