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Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [ 1 ] Gradually joint pain may develop, which may limit the person's ability to move. [ 1 ]
Necrotic bone and inflammation histology slide. The current etiology or origin of this disease is unknown. Some studies theorized that bone remodeling is maintained in a microenvironment in the FH meaning that there is a greater local component to changes to the femoral head than the normal systemic way that bone remodeling is handled throughout the body.
Dysbaric osteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N 2) embolism (blockage of the blood vessels by a bubble of nitrogen coming out of solution) in divers. [1] Although the definitive pathologic process is poorly understood, there are several ...
Complications may include nonunion of the fracture, avascular necrosis of the proximal part of the bone, and arthritis. [2] [1] Scaphoid fractures are most commonly caused by a fall on an outstretched hand. [2] Diagnosis is generally based on a combination of clinical examination and medical imaging. [2] Some fractures may not be visible on ...
Specifically, Kienböck's disease is another name for avascular necrosis [2] (death and fracture of bone tissue due to interruption of blood supply) with fragmentation and collapse of the lunate. This has classically been attributed to arterial disruption, but may also occur after events that produce venous congestion with elevated interosseous ...
[3] [5] The third (middle finger) metacarpal head has been reported to be the most common site of necrosis. [6] Though osteonecrosis is a fairly common condition, many cases of avascular necrosis of the metacarpal head go without being diagnosed. This is because presentation of symptoms is variable depending on the patient.
Preiser disease, or avascular necrosis of the scaphoid, is a rare condition where ischemia and necrosis of the scaphoid bone occurs without previous fracture.It is thought to be caused by repetitive microtrauma or side effects of drugs (e.g., steroids or chemotherapy) in conjunction with existing defective vascular supply to the proximal pole of the scaphoid.
Often, the body will try to create new bone around the area of necrosis. The resulting new bone is often called an involucrum. [13] On histologic examination, these areas of necrotic bone are the basis for distinguishing between acute osteomyelitis and chronic osteomyelitis. Osteomyelitis is an infective process that encompasses all of the bone ...