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Villoglandular adenocarcinoma of the cervix is a rare type of cervical cancer that, in relation to other cervical cancers, is typically found in younger women and has a better prognosis. [1] A similar lesion, villoglandular adenocarcinoma of the endometrium, may arise from the inner lining of the uterus, the endometrium. [2]
Tubular adenomas (tube-like shape) are the most common of the adenomatous polyps; they may occur everywhere in the colon and they are the least likely colon polyps to develop into colon cancer; Tubulovillous; Villous adenomas are commonly found in the rectal area and they are normally larger in size than the other two types of adenomas.
A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. [1] [2] [3] Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer.
Low to high grade dysplasia [13] Over 75% of volume has tubular appearance. [14] Tubulovillous adenoma: 20% to 25% [15] 25–75% villous [14] Villous adenoma: 15% [16] to 40% [15] Over 75% villous [14] Sessile serrated adenoma (SSA) [17] Basal dilation of the crypts; Basal crypt serration; Crypts that run horizontal to the basement membrane ...
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
Cervical cancer is a type of gynecological cancer that begins from cells lining the cervix, the lower part of the uterus. [14] Cervical cancer begins when the cells that line the cervix become abnormal and grow in a pattern that is atypical for non-cancerous cells. [14] Cervical cancer is typically first identified with an abnormal pap smear. [14]
Clear-cell adenocarcinoma of the vagina (and/or cervix) is a rare adenocarcinoma often linked to prenatal exposure to diethylstilbestrol (DES), a drug which was prescribed in high-risk pregnancy. Presentation
High-grade squamous intraepithelial lesion (HSIL or HGSIL) indicates moderate or severe cervical intraepithelial neoplasia or carcinoma in situ. It is usually diagnosed following a Pap test. In some cases these lesions can lead to invasive cervical cancer, if not followed appropriately. [citation needed] HSIL does not mean that cancer is present.