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  2. Fatty acid synthesis - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_synthesis

    In biochemistry, fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway.

  3. Essential fatty acid - Wikipedia

    en.wikipedia.org/wiki/Essential_fatty_acid

    Essential fatty acids, or EFAs, are fatty acids that are required by humans and other animals for normal physiological function that cannot be synthesized in the body. [1] [2] ⁠ As they are not synthesized in the body, the essential fatty acids – alpha-linolenic acid (ALA) and linoleic acid – must be obtained from food or from a dietary supplement.

  4. Acetate pathway - Wikipedia

    en.wikipedia.org/wiki/Acetate_pathway

    The acetate pathway, also known as the polyketide pathway, is a fundamental biosynthetic route in organisms for the production of fatty acids and polyketides. This pathway operates at the interface of central metabolism and specialized metabolite synthesis, playing a crucial role in the synthesis of both primary and secondary metabolites. [2 ...

  5. Essential fatty acid interactions - Wikipedia

    en.wikipedia.org/wiki/Essential_fatty_acid...

    Two classes of fatty acids are considered essential, the omega-3 and omega-6 fatty acids. Essential fatty acids are necessary for humans but cannot be synthesized by the body and must therefore be obtained from food. Omega-3 and omega-6 are used in some cellular signaling pathways and are involved in mediating inflammation, protein synthesis ...

  6. Citrate–malate shuttle - Wikipedia

    en.wikipedia.org/wiki/Citrate–malate_shuttle

    Cytosolic citrate, meaning citrate in the cytosol, is a key substrate for the generation of energy. It releases acetyl-CoA and provides NADPH for fatty acid synthesis, and, in subsequent pathways, generates NAD + for glycolysis. Citrate also activates acetyl-CoA carboxylase, an enzyme that is essential in the fatty acid synthesis pathway. [11]

  7. Lipogenesis - Wikipedia

    en.wikipedia.org/wiki/Lipogenesis

    Fatty acid synthesis starts with acetyl-CoA and builds up by the addition of two-carbon units. Fatty acid synthesis occurs in the cytoplasm of cells while oxidative degradation occurs in the mitochondria. Many of the enzymes for the fatty acid synthesis are organized into a multienzyme complex called fatty acid synthase. [5]

  8. Category:Essential fatty acids - Wikipedia

    en.wikipedia.org/wiki/Category:Essential_fatty_acids

    Print/export Download as PDF; Printable version; Help. Pages in category "Essential fatty acids" The following 5 pages are in this category, out of 5 total. ...

  9. Fatty acid synthase - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_synthase

    n/a n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of two ...