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Common side effects of morphine include drowsiness, euphoria, nausea, dizziness, sweating, and constipation. [12] Potentially serious side effects of morphine include decreased respiratory effort, vomiting, and low blood pressure. [12] Morphine is highly addictive and prone to abuse. [12]
Morphine is effective in relieving cancer pain, [38] although oxycodone shows superior tolerability and analgesic effect, though cost may limit its value in certain healthcare systems. [39] Side effects of nausea and constipation are rarely severe enough to warrant stopping of treatment. [38]
A 2016 Cochrane review (updated in 2021) found little difference in benefit between hydromorphone and other opioids for cancer pain. [10] Common side effects include dizziness, sleepiness, nausea, itchiness, and constipation. [7] Serious side effects may include abuse, low blood pressure, seizures, respiratory depression, and serotonin syndrome ...
In European nations such as Austria, Bulgaria, and Slovakia, slow-release oral morphine formulations are used in opiate substitution therapy (OST) for patients who do not well tolerate the side effects of buprenorphine or methadone. Buprenorphine can also be used together with naloxone for a longer treatment of addiction. In other European ...
Evidence suggests that cancer patients may develop the side effects of nausea and vomiting in anticipation of chemotherapy. In some patients, re-exposure to cues such as smell, sounds or sight associated with the clinic or previous treatment may evoke anticipatory nausea and vomiting. [6]
In addition, what appears to be opioid tolerance can be caused by opioid-induced hyperalgesia lowering the baseline pain level, thus masking the drug's analgesic effects. [11] Identifying the development of hyperalgesia is of great clinical importance since patients receiving opioids to relieve pain may paradoxically experience more pain as a ...
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.
Nicomorphine's side effects are similar to those of other opioids and include itching, nausea and respiratory depression.It is considered by doctors to be one of the better analgesics for the comprehensive mitigation of suffering, as opposed to purely clouding the noxious pain stimulus, in the alleviation of chronic pain conditions.