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Much of the synchronous bursting activity associated with interictal epileptiform activity appears to be generated in CA3. Its excitatory collateral connectivity seems to be mostly responsible for this. CA3 uniquely, has pyramidal cell axon collaterals that ramify extensively with local regions and make excitatory contacts with them.
They send an inhibitory axon to synapse with the cell body of the initial alpha neuron and/or an alpha motor neuron of the same motor pool. In this way, the Renshaw cell action represents a negative feedback mechanism. A Renshaw cell may be supplied by more than one alpha motor neuron collateral and it may synapse on multiple motor neurons.
An axon can divide into many branches called telodendria (Greek for 'end of tree'). At the end of each telodendron is an axon terminal (also called a terminal bouton or synaptic bouton, or end-foot). [20] Axon terminals contain synaptic vesicles that store the neurotransmitter for release at the synapse. This makes multiple synaptic connections ...
The axon reflex was discovered by Kovalevskiy and Sokovnin, two Russian scientists in 1873. [5] They described the axon reflex as a new type of peripheral (or local) reflex where electrical signal starts in the middle of the axon and transmit immediately skipping both an integration center and a chemical synapse as typically observed in the spinal cord reflex.
An extreme example of his precociousness and rebelliousness at the age of eleven is his 1863 imprisonment ... Golgi method. -a, axon; b, recurrent collateral; c and d ...
Axon terminals (also called terminal boutons, synaptic boutons, end-feet, or presynaptic terminals) are distal terminations of the branches of an axon. An axon, also called a nerve fiber, is a long, slender projection of a nerve cell that conducts electrical impulses called action potentials away from the neuron's cell body to transmit those ...
By adulthood, CA3 recurrent network activity is reduced, the frequency of spontaneous action potentials is decreased in Schaffer collaterals, and a single release locus synapse with one dendritic spine on a given CA1 pyramidal neuron can be developed by Schaffer collateral axons. [2]
A neural pathway connects one part of the nervous system to another using bundles of axons called tracts. The optic tract that extends from the optic nerve is an example of a neural pathway because it connects the eye to the brain; additional pathways within the brain connect to the visual cortex.