Search results
Results from the WOW.Com Content Network
Additionally, certain symptoms, including elevated swelling, paleness, narrower arteries, and hemorrhages, were more common in NAION than in optic neuritis. [ 49 ] The natural progression of NAION following acute vision loss typically includes an improvement in visual acuity by 3 or more lines on the Early Treatment Diabetic Retinopathy Study ...
The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1] However, the presence of larger and more numerous drusen in the macula is a common early sign of age-related macular degeneration (AMD).
Motor symptoms seem to be more predominant than sensory symptoms. [2] Symptoms of these disorders include: fatigue, pain, lack of balance, lack of feeling, lack of reflexes, and lack of sight and hearing, which result from muscle atrophy. Patients can also have high arched feet, hammer toes, foot drop, foot deformities, and scoliosis.
In children, optic disc drusen are usually buried and undetectable by fundoscopy except for a mild or moderate elevation of the optic disc. With age, the overlying axons become atrophied and the drusen become exposed and more visible. They may become apparent with an ophthalmoscope and some visual field loss at the end of adolescence. [7]
Foot drop can be managed with ankle-foot orthoses or surgical tendon transfer, [8] in which the tibialis posterior muscle is repurposed to function as a tibialis anterior muscle. In select types of distal myopathy, evaluation of the heart may be indicated. [8] Scoliosis and contractures can be surgically managed. [8]
Severity of symptoms can vary greatly between individuals and throughout the lives of the individuals themselves. This may be partly because there are over 130 currently known different mutations that can cause the disorder, each with their own specifics, and also because myotonia congenita is an ion channel disorder, and ion channels are ...
Early recognition is crucial given risks for severe visual loss and because it is treatable with immunosuppressive treatment such as steroids [3] or B-cell depleting therapy. [4] Relapse that occurs after reducing or stopping steroids is a characteristic feature. [3]
The common symptoms in all reported cases of primrose syndrome include ossified pinnae, learning disabilities or intellectual disability, hearing problems, movement disorders (ataxia, paralysis, and parkinsonism among others—likely due, in part, to calcification of the basal ganglia), a torus palatinus (a neoplasm on the mouth's hard palate), muscle atrophy, and distorted facial features.