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During pregnancy, the glands and blood vessels in the endometrium further increase in size and number. Vascular spaces fuse and become interconnected, forming the placenta , which supplies oxygen and nutrition to the embryo and fetus .
The decidua is the modified mucosal lining of the uterus (that is, modified endometrium) that forms every month, in preparation for pregnancy. It is shed off each month when there is no fertilized egg to support. [1] The decidua is under the influence of progesterone. Endometrial cells become highly characteristic.
The myometrium is made of smooth tissue and the endometrium lines the uterus. The endometrium is important in pregnancy because it is involved in the development of the placenta and it is where the fertilized egg implants itself during pregnancy. [2] In the endometrium there are endometrial arteries which are also known as spiral arteries.
The upper parts of the uterus remain separate, but the lower parts are fused into a single structure. Found in dogs, pigs, elephants, whales, dolphins, [37] and tarsiers, and strepsirrhine primates among others. Simplex The entire uterus is fused into a single organ. [35] Found in higher primates (including humans and chimpanzees).
The uterus or womb is the major female reproductive organ. The uterus provides mechanical protection, nutritional support, and waste removal for the developing embryo (weeks 1 to 8) and fetus (from week 9 until the delivery). In addition, contractions in the muscular wall of the uterus are important in pushing out the fetus at the time of birth.
Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy. This includes morphological and functional changes (the decidual reaction) to endometrial stromal cells (ESCs), the presence of decidual white blood cells (leukocytes), and vascular changes to maternal arteries.
Extravillous trophoblasts grow out from the placenta and penetrate into the decidualized uterus. This process is essential not only for physically attaching the placenta to the mother, but also for altering the vasculature in the uterus. This alteration allows an adequate blood supply to the growing fetus as pregnancy progresses.
The endometrium (from the mother) over the chorion frondosum (this part of the endometrium is called the decidua basalis) forms the decidual plate. The decidual plate is tightly attached to the chorion frondosum and goes on to form the actual placenta. Endometrium on the opposite side to the decidua basalis is the decidua parietalis.