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4-Hydroxyphenylglycine (HPG) is a non-proteogenic amino acid found in vancomycin and related glycopeptides. HPG is synthesized from the shikimic acid pathway and requires four enzymes to synthesize: [ 1 ] Both L - and D -HPG are used in the vancomycin class of antibiotics.
Side effects associated with ospemifene include vaginal discharge, hot flashes, and diaphoresis. [8] More serious adverse effects are similar to those of estrogens and estrogen receptor modulators. These include, but are not limited to, thromboembolism, allergic reactions, fatigue, and headache, and others could occur. [ 8 ]
(S)-DHPG has been investigated for therapeutic effects in the treatment of neuronal injury (such as those associated with ischemia or hypoxia), cognitive enhancement, and Alzheimer's disease. [1] 3,5-Dihydroxyphenylglycine can be isolated from the latex of Euphorbia helioscopia. [2] DHGP is also found in vancomycin and related glycopeptides.
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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
Side effects of relugolix include menstrual abnormalities, hot flashes, excessive sweating, headache, and decreased bone mineral density. [ 7 ] [ 1 ] Relugolix is a GnRH antagonist, or an antagonist of the gonadotropin-releasing hormone receptor . [ 1 ]
Side effects of droxidopa include headache, dizziness, nausea, and hypertension, among others. [2] Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine (noradrenaline). [4] Hence, it acts as a non-selective agonist of the α-and β-adrenergic receptors.