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They are mostly caused by low levels of female sex hormones (e.g. estrogens) that occur during menopause. [1] [2] Estrogens and progestogens are the main hormone drugs used in HRT. Progesterone is the main female sex hormone that occurs naturally and is also manufactured into a drug that is used in menopausal hormone therapy. [1]
Other medication such as Tibolone - which works by mimicking the activity of oestrogen and progesterone - or certain anti-depressants may help, although there can be side effects to taking these.
Doctors typically also prescribe progesterone to women who still have a uterus, since the progesterone can be protective. This is sometimes called combination therapy, since it combines both ...
‘This is unlike oestrogen and progesterone, which plummet [during] menopause.’ As you’ll almost certainly be aware, HRT is now as staple a part of a menopausal woman’s daily routines as ...
If progesterone is taken by mouth or at high doses, certain central side effects including sedation, sleepiness, and cognitive impairment can also occur. [ 28 ] [ 20 ] The medication is a naturally occurring progestogen and hence is an agonist of the progesterone receptor (PR), the biological target of progestogens like endogenous progesterone ...
More serious side effects include bone loss, blood clots, allergic reactions, and liver problems. [10] Use is not recommended during pregnancy as it may harm the baby . [ 10 ] MPA is an artificial progestogen , and as such activates the progesterone receptor , the biological target of progesterone . [ 4 ]
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