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If left untreated, aspiration pneumonia can progress to form a lung abscess. [5] Another possible complication is an empyema, in which pus collects inside the lungs. [6] If continual aspiration occurs, the chronic inflammation can cause compensatory thickening of the insides of the lungs, resulting in bronchiectasis. [6]
Aspiration pneumonitis (Mendelson's syndrome) is chemical injury of lung tissue secondary to aspiration of regurtitated gastric acid. [15] The syndrome was first described among pregnant patients [16] after the administration of anesthesia, though it can occur in any scenario where gastric contents are aspirated. [17]
Treatment is focused on reversing the cause of inflammation and reducing symptoms. Corticosteroids may be given to reduce inflammation, often before long-term scarring occurs. Antibiotics are usually not helpful or needed, unless there is a secondary infection. Oxygen therapy may be helpful.
Acid consumption from poisoning such as methanol ingestion, elevated levels of iron in the blood, and chronically decreased production of bicarbonate may also produce metabolic acidosis. Metabolic acidosis is compensated for in the lungs, as increased exhalation of carbon dioxide promptly shifts the buffering equation to reduce metabolic acid.
Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...
Acid reflux, also known as gastroesophageal reflux disease, is a common condition that causes acid to splash from the stomach into the esophagus. The result: telltale symptoms of chest pain ...
Mendelson's syndrome, named in 1946 for American obstetrician and cardiologist Curtis Lester Mendelson, is a form of chemical pneumonitis or aspiration pneumonitis caused by aspiration of stomach contents (principally gastric acid) during anaesthesia in childbirth.
Lactic acidosis is commonly found in people who are unwell, such as those with severe heart and/or lung disease, a severe infection with sepsis, the systemic inflammatory response syndrome due to another cause, severe physical trauma, or severe depletion of body fluids. [3]