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However, some tailed bacteriophage genomes can vary quite significantly in nucleotide sequence, even among the same genus. Due to their characteristic structure and possession of potentially homologous genes, it is believed these bacteriophages possess a common origin.
An example of a bacteriophage known to follow the lysogenic cycle and the lytic cycle is the phage lambda of E. coli. [53] Sometimes prophages may provide benefits to the host bacterium while they are dormant by adding new functions to the bacterial genome, in a phenomenon called lysogenic conversion.
Bacteriophage Lambda Structure at Atomic Resolution [1] Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. [2]
The phage tail-like tubule of the T6SS assembles on a structure analogous to bacteriophage baseplates. It consists of the proteins TssE, TssF, TssG, and TssK. The baseplate and phage tail-like complex interact in the bacterial cytoplasm, and then are recruited to the cell envelope by the membrane complex. [10]
[8] [9] The molecular structure of Ff phages was determined using a number of physical techniques, especially X-ray fiber diffraction, [2] [6] solid-state NMR and cryo-electron microscopy. [10] The structures of the phage capsid and of some other phage proteins are available from the Protein Data Bank. [6]
Schematic drawing of a Φ29 phage virion (cross section and side view). The structure of Φ29 is composed of seven main proteins: the terminal protein (p3), the head or capsid protein (p8), the head or capsid fiber protein (p8.5), the distal tail knob (p9), the portal or connector protein (p10), the tail tube or lower collar proteins (p11), and the tail fibers or appendage proteins (p12*).
Tailed bacteriophage structure: (1) head, (2) tail, (3) DNA, (4) capsid, (5) collar, (6) sheath, (7) tail fibres, (8) spikes, (9) base plate. In some groups of viruses—such as the class Caudoviricetes ("tail viruses") and the genus Tupanvirus—the capsid carries an appendage called the "tail". The tail of the Caudoviricetes is usually ...
An example of a virus that uses the lysogenic cycle to its advantage is the Herpes Simplex Virus. [10] After first entering the lytic cycle and infecting a human host, it enters the lysogenic cycle. This allows it to travel to the nervous system's sensory neurons and remain undetected for long periods of time.