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Reticular fibers, reticular fibres or reticulin is a type of fiber in connective tissue [1] composed of type III collagen secreted by reticular cells. [2] They are mainly composed of reticulin protein and form a network or mesh.
[23]: 171 They are found in the walls of large blood vessels and in certain ligaments, particularly in the ligamenta flava. [23]: 173 In hematopoietic and lymphatic tissues, reticular fibers made by reticular cells provide the stroma—or structural support—for the parenchyma (that is, the bulk of functional substance) of the organ.
Reticular connective tissue resembles areolar connective tissue, but the only fibers in its matrix are reticular fibers, which form a delicate network along which fibroblasts called reticular cells lie scattered. Although reticular fibers are widely distributed in the body, reticular tissue is limited to certain sites. It forms a labyrinth-like ...
A reticular cell is a type of fibroblast that synthesizes collagen alpha-1(III) and uses it to produce extracellular reticular fibers.Reticular cells provide structural support, since they produce and maintain the thin networks of fibers that are a framework for most lymphoid organs.
Its fibers run in random directions and are mostly collagenous, but elastic and reticular fibers are also present. Areolar tissue is highly variable in appearance. In many serous membranes , it appears as a loose arrangement of collagenous and elastic fibers, scattered cells of various types; abundant ground substance ; numerous blood vessels.
The reticular theory predominated until the 1890s when Ramon y Cajal brought forth his neuron doctrine of synaptic junctions, which in essence replaced the reticular theory. Gerlach was one of the first physicians to use photomicrography for medical research.
Reticular theory is an obsolete scientific theory in neurobiology that stated that everything in the nervous system, such as the brain, is a single continuous network. The concept was postulated by a German anatomist Joseph von Gerlach in 1871, and was most popularised by the Nobel laureate Italian physician Camillo Golgi .
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...