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In cell biology, protein turnover refers to the replacement of older proteins as they are broken down within the cell. Different types of proteins have very different turnover rates. A balance between protein synthesis and protein degradation is required for good health and normal protein metabolism.
Tumor characteristics: Tumors with a high cell turnover rate, rapid growth rate, and high tumor bulk tend to be more associated with the development of tumor lysis syndrome. The most common tumors associated with this syndrome are poorly differentiated lymphomas (such as Burkitt's lymphoma ), other Non-Hodgkin Lymphomas (NHL), acute ...
Cell turnover, the replacement of old cells with newly generated ones; Lake turnover, when the waters in a lake ecosystem begin to mix again to create a uniform temperature; Population turnover, measure of gross moves in relation to the size of a population; Substance turnover, or biogeochemical cycle, a pathway by which a chemical substance moves
In biochemistry, metabolic flux (often referred to as flux) is the rate of turnover of molecules through a metabolic pathway. Flux is regulated by the enzymes involved in a pathway. Within cells, regulation of flux is vital for all metabolic pathways to regulate the pathway's activity under different conditions. [1]
"By triggering the body’s natural wound-healing process, the skin cell turnover rate is increased, sloughing off dead, pigmented cells to allow for new, healthy skin cells to be brought to the ...
In chemistry, the term "turnover number" has two distinct meanings. In enzymology , the turnover number ( k cat ) is defined as the limiting number of chemical conversions of substrate molecules per second that a single active site will execute for a given enzyme concentration [ E T ] for enzymes with two or more active sites. [ 1 ]
The researchers found that the bladder cancer cells grew at a “much faster” rate in mice that had fewer Y chromosomes compared to those with many, according to the release.
For example, yeast cells expressing a protein substrate of interest typically require cycloheximide chases lasting up to 90 minutes to allow protein turnover to occur. [4] [7] In contrast, proteins that are expressed in mammalian cell lines tend to me more stable at steady state and may require a chase lasting 3 to 8 hours.