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This area may feel hard, warm, and tender. The skin around the vein may be itchy and swollen. The area may begin to throb or burn. Symptoms may be worse when the leg is lowered, especially when first getting out of bed in the morning. A low-grade fever may occur. Sometimes phlebitis may occur where a peripheral intravenous line was started.
Thrombophlebitis is a phlebitis (inflammation of a vein) related to a thrombus (blood clot). [2] When it occurs repeatedly in different locations, it is known as thrombophlebitis migrans ( migratory thrombophlebitis ).
Ultrasound is indicated if superficial phlebitis involves or extends into the proximal one-third of the medial thigh, there is evidence for clinical extension of phlebitis, lower extremity swelling is greater than would be expected from a superficial phlebitis alone or diagnosis of superficial thrombophlebitis in question. [11]
Infiltration is the diffusion or accumulation (in a tissue or cells) of foreign substances in amounts excess of the normal. The material collected in those tissues or cells is called infiltrate . Definitions of infiltration
Infection, phlebitis, extravasation, infiltration, air embolism, hemorrhage (bleeding) and formation of a hematoma (bruise) may occur. A catheter embolism may occur when a small part of the cannula breaks off and flows into the vascular system. When removing a peripheral IV cannula, the tip should be inspected to ensure it's intact.
When the leakage is not of harmful consequence it is known as infiltration. Extravasation of medication during intravenous therapy is an adverse event related to therapy that, depending on the medication, amount of exposure, and location, can potentially cause serious injury and permanent harm, such as tissue necrosis.
The infiltration of white blood cells and activation of dermal macrophages mediated by the release of pro-inflammatory chemicals can facilitate the wound healing process. Dermal macrophages are primarily populated in the dermis of the skin as they are specialised in skin homeostasis and repair.
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.