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InterPro is a database of ... Protein classification system is a network with multiple levels of sequence diversity from superfamilies to subfamilies that reflects ...
The general purpose of the Pfam database is to provide a complete and accurate classification of protein families and domains. [5] Originally, the rationale behind creating the database was to have a semi-automated method of curating information on known protein families to improve the efficiency of annotating genomes. [6]
InterPro In biochemistry and medicine , glycoprotein IIb/IIIa ( GPIIb/IIIa , also known as integrin α IIb β 3 ) is an integrin complex found on platelets . It is a transmembrane receptor for fibrinogen [ 1 ] and von Willebrand factor , and aids platelet activation .
InterPro In molecular biology , the ferric uptake regulator family is a family of bacterial proteins involved in regulating metal ion uptake and in metal homeostasis . The family is named for its founding member, known as the ferric uptake regulator or ferric uptake regulatory protein ( Fur ).
InterPro In cell signalling , Son of Sevenless ( SOS ) refers to a set of genes encoding guanine nucleotide exchange factors that act on the Ras subfamily of small GTPases . History and name
Pharmacologists were able to use Microsoft Excel to compare chemical and genomic data related to the effectiveness of drugs. However, the industry has reached what is referred to as the Excel barricade. This arises from the limited number of cells accessible on a spreadsheet. This development led to the need for computational pharmacology.
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Immunoglobulin-like domains that are related in both sequence and structure can be found in several diverse protein families. Ig-like domains are involved in a variety of functions, including cell–cell recognition, cell-surface receptors, muscle structure and the immune system. [4]