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Severe side effects may include kidney problems. [2] Use in pregnancy appears to be safe. [2] It is a prodrug, which works after being converted to aciclovir in a person's body. [2] Valaciclovir was patented in 1987 and came into medical use in 1995. [3] [4] It is on the World Health Organization's List of Essential Medicines. [5]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
[6] [8] It appears to be safe during breastfeeding. [9] [10] Aciclovir is a nucleoside analogue that mimics guanosine. [6] It works by decreasing the production of the virus's DNA. [6] Aciclovir was patented in 1974 by Burroughs Wellcome and approved for medical use in 1981. [11] It is on the World Health Organization's List of Essential ...
The kidneys play a vital role in health, responsible for filtering harmful toxins out of our blood and regulating blood pressure. ... It is critical that this procedure be as safe as possible, as ...
A review that considered berberine’s effects on heart health found some studies supporting this claim, but due to the high risk of bias, the researchers recommended more clinical trials be ...
Below are the primetime rankers for broadcast, cable and premium cable networks in 2024, among total viewers (as well as the top 50 list in adults 18-49).
This drives sales of the more expensive me-too drug when both drugs have virtually identical safety profiles. Similarly, Valtrex, first FDA approved in 2001 to treat persistent herpes outbreaks is a prodrug of acyclovir, first FDA approved in the mid-1980s.
Image credits: Bored Panda #5 Megan Fox Allegedly Found “Upsetting” Messages On Mgk’s Phone. Machine Gun Kelly and Megan Fox have certainly been the talk of a lot of drama this year. Back in ...