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An ameboma, also known as an amebic granuloma, is a rare complication of Entamoeba histolytica infection, where in response to the infecting amoeba there is formation of annular colonic granulation, which results in a large local lesion of the bowel.
Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
E. histolytica infections occur in both the intestine and (in people with symptoms) in tissue of the intestine and/or liver. [14] Those with symptoms require treatment with two medications, an amoebicidal tissue-active agent and a luminal cysticidal agent. [9] Individuals that are asymptomatic only need a luminal cysticidal agent. [7]
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]
However, due to the variety of treatment options and lifestyle factors, outcomes of individual treatments and form of management vary. A high proportion of contact granulomas are present in patients with concurrent gastroesophageal reflux, and so treatment of the reflux is imperative. [3] Those caused by intubation trauma are less likely to ...
Tachosil may cause an allergic reaction, thrombosis (blood clots), a blockage in the intestine when used during abdominal surgeries, the formation of scar tissue and foreign body granuloma (a type of inflammatory reaction).
Vitamin D treatment may be associated with less inflammatory bowel disease reoccurrence of symptoms (relapse). It is not clear if this treatment improves the person's quality of life or what the clinical response to vitamin D treatment. The ideal treatment regime and dose of vitamin D therapy has not been well enough studied. [90]
In histology, cryptitis refers to inflammation of an intestinal crypt. Cryptitis is a non-specific histopathologic finding that is seen in several conditions, e.g. inflammatory bowel disease , [ 1 ] diverticular disease , [ 2 ] radiation colitis, [ 3 ] infectious colitis .