Ad
related to: can oxidative stress be reversed
Search results
Results from the WOW.Com Content Network
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
Cell damage (also known as cell injury) is a variety of changes of stress that a cell suffers due to external as well as internal environmental changes. Amongst other causes, this can be due to physical, chemical, infectious, biological, nutritional or immunological factors. Cell damage can be reversible or irreversible.
XthA (exonuclease III, a DNA repair enzyme) and KatE (catalase) are known to play important roles in the defense against oxidative stress but KatF regulon genes are not induced by oxidative stress. [2] There is an overlap between oxidative stress response and other regulatory networks like heat shock response, SOS response.
Research suggests that oxidative stress, which is caused by factors including sunlight, alcohol, and certain medications, plays a role in aging and the development of neurodegenerative diseases.
In cases where the free radical-induced chain reaction involves base pair molecules in a strand of DNA, the DNA can become cross-linked. [19] Oxidative free radicals, such as the hydroxyl radical and the superoxide radical, can cause DNA damages, and such damages have been proposed to play a key role in the aging of crucial tissues. [20]
Drinking enough water can reverse these effects and reduce the oxidative stress that exercise can cause. When working up a sweat, you’ll lose more water than usual. ...
While aging is the reason for gray hair and genetics being the most influential in terms of the timing, Dr. Gohara says oxidative stress, lifestyle factors, and even certain health conditions ...
But under oxidative stress conditions, excessive ROS can damage cellular proteins, lipids and DNA, leading to fatal lesions in the cell that contribute to carcinogenesis. Cancer cells exhibit greater ROS stress than normal cells do, partly due to oncogenic stimulation, increased metabolic activity and mitochondrial malfunction.
Ad
related to: can oxidative stress be reversed