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Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus. Most cases of endometrial hyperplasia result from high levels of estrogens , combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this ...
Adenomyosis is a medical condition characterized by the growth of cells that proliferate on the inside of the uterus (endometrium) atypically located among the cells of the uterine wall , [2] as a result, thickening of the uterus occurs. As well as being misplaced in patients with this condition, endometrial tissue is completely functional.
Although both classes of hormones can have symptomatic benefit, progestogen is specifically added to estrogen regimens, unless the uterus has been removed, to avoid the increased risk of endometrial cancer. Unopposed estrogen therapy promotes endometrial hyperplasia and increases the risk of cancer, while progestogen reduces this risk.
[6] [4] Due to diffuse polyposis typical presentation is that of a female (40-45 yrs) With a history of Amenorrhea for 2 weeks Followed by excessive menstrual bleeding cause being anovulation Histopathology: Proliferative endometrium without atypical changes Swiss cheese appearance On USG increased endometrial thickness without atypical change
Under the influence of estrogen the endometrium (uterine lining) is stimulated and eventually such lining will be shed off (estrogen breakthrough bleeding). The anovulation chapter discusses its multiple possible causes. Longstanding anovulation can also lead to endometrial hyperplasia and facilitate the development of endometrial cancer.
In the early stages of infection, the ultrasound may appear normal. As the disease progresses, nonspecific findings can include free pelvic fluid, endometrial thickening, uterine cavity distension by fluid or gas. In some instances the borders of the uterus and ovaries appear indistinct.
Changes in sexual health: Lower estrogen levels can lead to low libido, more trouble achieving orgasm and vaginal dryness, which can cause burning and pain during sex, Tang says. Many women find ...
Endometrial tissue most often grows on or around reproductive organs such as the ovaries and fallopian tubes, on the outside surface of the uterus, or on the tissues surrounding the uterus and the ovaries . [3] It can also grow on other organs in the pelvic region like the bowels, stomach, bladder, or the cervix. [10]