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Most toothpastes contains between 0.22% (1,000 ppm) and 0.312% (1,450 ppm) fluoride, usually in the form of sodium fluoride, stannous fluoride, or sodium monofluorophosphate (MFP). Frequent use of toothpaste with 1,100 ppm fluoride content enhances the remineralization of enamel and inhibits the demineralization of enamel and root surfaces. [34]
Fluoride-containing toothpaste can be classified into two types, namely low-fluoride and high-fluoride toothpaste. [12] Low-fluoride toothpaste, depending on brand, generally contains 0.22% to 0.31% fluoride. [12] These fluorides are often manufactured in the form of sodium fluoride, stannous fluoride, or sodium monofluorophosphate (MFP). [4]
Sodium monofluorophosphate is produced industrially by the reaction of sodium fluoride with sodium metaphosphate: [2] NaPO 3 + NaF → Na 2 PO 3 F. The process involves scission of a pyrophosphate bond, analogous to hydrolysis. SMFP can also be prepared by treating tetrasodium pyrophosphate or disodium phosphate with hydrogen fluoride. [2]
Regular use of a fluoridated toothpaste has been shown to provide a significant source of fluoride to the mouth by the means of direct fluoride contact to tooth structure. [20] The types of fluoride added to toothpaste include: sodium fluoride , sodium monofluorophosphate (MFP), and stannous fluoride .
The additional fluoride in toothpaste has beneficial effects on the formation of dental enamel and bones. Sodium fluoride (NaF) is the most common source of fluoride, but stannous fluoride (SnF 2), and sodium monofluorophosphate (Na 2 PO 3 F) are also used. [12]
Sensodyne is a brand of toothpaste that was first sold by Block Drug, a Brooklyn, New York-based company established in 1907 by pharmacist Alexander Block. [1] By 1925, manufacturing dental care products had become the company's focus. Leonard N. Block followed his father into the family business which relocated to Jersey City, New Jersey, in 1938.
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