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Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes , some having protective effect, with each gene having its own tendency to be influenced by the environment although a ...
AERD affects an estimated 0.3–0.9% of the general population in the US, including around 7% of all asthmatics, about 14% of adults with severe asthma, and ~5-10% of patients with adult onset asthma. [2] [3] [8] AERD is uncommon among children, with around 6% of patients, predominantly female, reporting disease onset during childhood. [9]
Acute severe asthma, previously known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators and corticosteroids. [115] Half of cases are due to infections with others caused by allergen, air pollution, or insufficient or inappropriate medication use.
The symptoms of VCD are often inaccurately attributed to asthma, [5] which in turn results in the unnecessary and futile intake of corticosteroids, bronchodilators and leukotriene modifiers, [7] although there are instances of comorbidity of asthma and VCD. [16] The differential diagnosis for vocal cord dysfunction includes vocal fold swelling ...
Patients may experience dizziness, heart palpitations, hyperglycemia, diarrhea and muscle cramps when taking these medications. Importantly, medications that antagonize the β2 receptor (β-blockers) may significantly increase the risk of asthma exacerbations, and are generally avoided in asthmatic patients. [7]
Because of the wide differential diagnosis of exertional respiratory complaints, the diagnosis of exercise-induced bronchoconstriction based on history and self-reported symptoms alone has been shown to be inaccurate [6] [7] and to result in an incorrect diagnosis more than 50% of the time. [8]
The goal of asthmatic agents is to reduce asthma exacerbation frequencies and related hospital visits. Anti-asthmatic agents as rescue medications for acute asthma attacks include short-acting β 2-adrenergic receptor agonists (SABA), short-acting muscarinic antagonists (SAMA), systemic glucocorticoids, and magnesium sulfate.
A wheeze is a clinical symptom of a continuous, coarse, whistling sound produced in the respiratory airways during breathing. [1] For wheezes to occur, part of the respiratory tree must be narrowed or obstructed (for example narrowing of the lower respiratory tract in an asthmatic attack), or airflow velocity within the respiratory tree must be heightened.