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Corneal cross-linking (CXL) with riboflavin (vitamin B 2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. [2]
The National Eye Institute reports keratoconus is the most common corneal dystrophy in the United States, affecting about one in 2,000 Americans, [77] [78] but some reports place the figure as high as one in 500. [79] In the pediatric populations, ages three to 18, the prevalence of keratoconus was found to be as high as one in 334 children. [80]
Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue (the graft). When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty .
Long-term contact lens use can lead to alterations in corneal thickness, stromal thickness, curvature, corneal sensitivity, cell density, and epithelial oxygen uptake. . Other structural changes may include the formation of epithelial vacuoles and microcysts (containing cellular debris), corneal neovascularization, as well as the emergence of polymegethism in the corneal endoth
Keratoconus, a progressive, noninflammatory, bilateral, asymmetric disease, characterized by paraxial stromal thinning and weakening that leads to corneal surface distortion. [2] Keratoglobus, a rare noninflammatory corneal thinning disorder, characterised by generalised thinning and globular protrusion of the cornea. [3]
Keratoconus, a progressive thinning of the cornea, is a common corneal disorder. Keratoconus occurring after refractive surgery is called Corneal Ectasia. It is believed that additional thinning of the cornea via refractive surgery may contribute to advancement of the disease [31] that may lead to the need for a corneal transplant.
A lamellar disc from a donor cornea is placed over the de-epithelialized host cornea and sutured into a prepared groove on the host cornea. Indications include treatment of keratoconus, refractive errors like myopia and high hypermetropia including aphakia, which cannot be corrected with conservative methods. [2]
Cross-link, a chemical bond of one polymer chain to another Corneal collagen cross-linking , a parasurgical treatment for corneal ectasia and keratoconus Topics referred to by the same term