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Neosalvarsan is a synthetic chemotherapeutic that is an organoarsenic compound.It became available in 1912 and superseded the more toxic and less water-soluble Salvarsan as an effective treatment for syphilis.
Arsphenamine was used to treat the disease syphilis because it is toxic to the bacterium Treponema pallidum, a spirochete that causes syphilis. [6] Arsphenamine was originally called "606" because it was the sixth in the sixth group of compounds synthesized for testing; it was marketed by Hoechst AG under the trade name "Salvarsan" in 1910.
Aug. 20—Amid a local and national surge of syphilis, the U.S. Food and Drug Administration this month approved an over-the-counter test for the sexually transmitted infection. While some may ...
Common symptoms that develop over the first couple of years of life include enlargement of the liver and spleen (70%), rash (70%), fever (40%), neurosyphilis (20%), and lung inflammation (20%). [7] If untreated, late congenital syphilis may occur in 40%, including saddle nose deformation, Higouménakis' sign , saber shin , or Clutton's joints ...
A staggering 207,000 syphilis cases were reported in the US in 2022 — an 80% increase since 2018. Syphilis cases soar to highest level in 70 years — CDC sounds alarm over ‘unacceptable’ crisis
In 2022, there were more than 207,000 total syphilis cases reported, the highest number since the 1950s, according to the CDC. Syphilis is a bacterial infection that may appear minor at first. In ...
[68] [69] [70] The outer membrane of T. pallidum has too few surface proteins for an antibody to be effective. Efforts to develop a safe and effective syphilis vaccine have been hindered by uncertainty about the relative importance of humoral and cellular mechanisms to protective immunity, [ 71 ] and because T. pallidum outer membrane proteins ...
Although infections like chlamydia, for example, are highest among adolescents and young adults, a new research review presented at the European Congress of Clinical Microbiology and Infectious ...
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