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Legionella is a genus of gram-negative bacteria that can be seen using a silver stain or grown in a special media that contains cysteine, an amino acid.It is known to cause legionellosis [3] (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. [3]
Legionella pneumophila, the primary causative agent for Legionnaire's disease, is an aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium. [ 1 ] [ 2 ] L. pneumophila is a intracellular parasite that preferentially infects soil amoebae and freshwater protozoa for replication.
The number of cases that occur globally is not known. [1] Legionnaires' disease is the cause of an estimated 2–9% of pneumonia cases that are acquired outside of a hospital. [1] An estimated 8,000 to 18,000 cases a year in the United States require hospitalization. [9] Outbreaks of disease account for a minority of cases.
Year City Venue Source Cases Deaths Fatality rate Notes 2000: Melbourne, Australia: Sea Life Melbourne Aquarium: Cooling tower: 125: 4: 3.2%: In April 2000, an outbreak of Legionella pnemophila serogroup 1 occurred in Melbourne, Australia. The outbreak resulted in 125 confirmed cases of Legionnaire's disease, with 95 (76%) hospitalised.
These include the Chlamydiaceae, Legionella and the Mycoplasmataceae (including mycoplasma and ureaplasma); the Spirochetes and Rickettsiaceae are also often considered atypical. [ 1 ] Gram-positive bacteria have a thick peptidoglycan layer in their cell wall, which retains the crystal violet during Gram staining, resulting in a purple color.
Legionella pneumophila is the most common cause, but sometimes other species of Legionella bacteria also cause Legionnaires' disease. [ 15 ] [ 16 ] The terms "Philadelphia fever" and "Legion fever" appear to have been used at the time of the outbreak and for shortly thereafter, [ 17 ] although at least one 2008 source which covers disease in a ...
Legionella micdadei is a Gram-negative bacterium from the genus Legionella, which stains acid-fast. It stains weakly, but loses this trait upon being grown in culture. Tatlockia micdadei is an alternative term for L. micdadei, the Pittsburgh pneumonia agent and TATLOCK strain. [2] It is named after Joseph E. McDade, who first isolated L ...
Pontiac fever is known to have a short incubation period of 1 to 3 days. No fatalities have been reported and cases resolve spontaneously without treatment. [8] It is often not reported. [9] Age, gender, and smoking do not seem to be risk factors. Pontiac fever seems to affect young people in the age medians of 29 to 32.