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Autosomal dominant and autosomal recessive inheritance, the two most common Mendelian inheritance patterns. An autosome is any chromosome other than a sex chromosome.. In genetics, dominance is the phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.
A heterozygote advantage describes the case in which the heterozygous genotype has a higher relative fitness than either the homozygous dominant or homozygous recessive genotype. Loci exhibiting heterozygote advantage are a small minority of loci. [1] The specific case of heterozygote advantage due to a single locus is known as overdominance.
The degree of dominance affects the relative importance of selection on heterozygotes versus homozygotes. If A is not completely dominant (i.e. h {\displaystyle h} is not close to zero), then deleterious mutations are primarily removed by selection on heterozygotes because heterozygotes contain the vast majority of deleterious B alleles ...
In genetics, underdominance, also known as homozygote advantage, heterozygote disadvantage, or negative overdominance," [1] is the opposite of overdominance. It is the selection against the heterozygote , causing disruptive selection [ 2 ] and divergent genotypes .
Alternatively, a heterozygote for gene "R" is assumed to be "Rr". The uppercase letter is usually written first. [citation needed] If the trait in question is determined by simple (complete) dominance, a heterozygote will express only the trait coded by the dominant allele, and the trait coded by the recessive allele will not be present.
Co-dominant expression of genes for plumage colours. In cases of co-dominance, the genetic traits of both different alleles of the same gene-locus are clearly expressed in the phenotype. For example, in certain varieties of chicken, the allele for black feathers is co-dominant with the allele for white feathers.
The principle of dominant inheritance discovered by Mendel states that in a heterozygote the dominant allele will cause the recessive allele to be "masked": that is, not expressed in the phenotype. Only if an individual is homozygous with respect to the recessive allele will the recessive trait be expressed.
Incomplete dominance is when the dominant allele and recessive allele come together to form a blend of the two phenotypes in the offspring. Test crosses are also not applicable with codominant genes, where both phenotypes of a heterozygote trait will be expressed.