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Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene ( c yc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism.
The researchers injected the oncogene into fertilized mouse eggs close to the one-cell stage and implanted them into a female host mouse where they developed to term. [5] The resulting offspring were then tested for the presence or absence of the oncogene. [5] Those with the gene are referred to as "founder" mice and are mated with unaltered ...
FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. [9] FOXM1-null mouse embryos were neonatal lethal as a result of the development of polyploid cardiomyocytes and hepatocytes, highlighting the role of FOXM1 in mitotic division.
66214 Ensembl ENSG00000102760 ENSMUSG00000022018 UniProt Q9H4X1 Q9DBX1 RefSeq (mRNA) NM_014059 NM_025427 RefSeq (protein) NP_054778 NP_079703 Location (UCSC) Chr 13: 41.46 – 41.47 Mb Chr 14: 79.53 – 79.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Regulator of cell cycle RGCC (RGCC) also known as response gene to complement 32 protein (RGC-32) is a protein that in humans is ...
C8orf34 is a protein that, in Homo sapiens, is encoded by the C8orf34 gene. [4] Aliases for C8orf34 include vestibule-1 or VEST-1. Within the cell, C8orf34 is localized to the nucleus and nucleoli where it may play a role in the regulation of gene expression as well as the cell cycle.
66953 Ensembl ENSG00000144354 ENSMUSG00000055612 UniProt Q9BWT1 Q9D0M2 RefSeq (mRNA) NM_031942 NM_145810 NM_025866 RefSeq (protein) NP_114148 NP_665809 NP_080142 Location (UCSC) Chr 2: 173.35 – 173.37 Mb Chr 2: 72.31 – 72.32 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cell division cycle-associated protein 7 is a protein that in humans is encoded by the CDCA7 gene. This gene ...
894 12444 Ensembl ENSG00000118971 ENSMUSG00000000184 UniProt P30279 P30280 RefSeq (mRNA) NM_001759 NM_009829 RefSeq (protein) NP_001750 NP_033959 Location (UCSC) Chr 12: 4.27 – 4.31 Mb Chr 6: 127.13 – 127.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. Function The protein encoded by this gene ...
The murine double minute (mdm2) oncogene, which codes for the Mdm2 protein, was originally cloned, along with two other genes (mdm1 and mdm3) from the transformed mouse cell line 3T3-DM. Mdm2 overexpression, in cooperation with oncogenic Ras , promotes transformation of primary rodent fibroblasts, and mdm2 expression led to tumor formation in ...