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  2. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    diltiazem verapamil The 8th Joint National Committee (JNC-8) recommends calcium channel blockers to be a first-line treatment either as monotherapy or in combination with thiazide -type diuretics, ACEis, or ARBs for all patients regardless of age or race.

  3. Diltiazem - Wikipedia

    en.wikipedia.org/wiki/Diltiazem

    Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. [9] It may also be used in hyperthyroidism if beta blockers cannot be used. [ 9 ]

  4. Generic drug - Wikipedia

    en.wikipedia.org/wiki/Generic_drug

    For example, as of 2006, diltiazem hydrochloride had four equivalence groups, all using the same active ingredient, but considered equivalent only within each group. [46] In order to start selling a drug promptly after the patent on innovator drug expires, a generic company has to file its ANDA well before the patent expires.

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  8. Calcium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Calcium_channel_blocker

    Structural formula of diltiazem. Benzothiazepine calcium channel blockers belong to the benzothiazepine class of compounds and are an intermediate class between phenylalkylamine and dihydropyridines in their selectivity for vascular calcium channels. By having both cardiac depressant and vasodilator actions, benzothiazepines are able to reduce ...

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