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The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
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Poliomyelitis, or polio, is a distinctly contagious illness caused by a virus called poliovirus. The virus targets the nervous system, which is why it sometimes triggers spinal and respiratory ...
A crease pattern (commonly referred to as a CP) [1] is an origami diagram that consists of all or most of the creases in the final model, rendered into one image. This is useful for diagramming complex and super-complex models, where the model is often not simple enough to diagram efficiently.
CD155 is a transmembrane protein with 3 extracellular immunoglobulin-like domains, D1-D3, where D1 is recognized by the virus. [8]Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy [9] while a high resolution structures of the ectodomain D1 and D2 of CD155 were solved by x-ray crystallography.
Non-polio enteroviruses, like EV-D68, cause about 10 to 15 million infections and tens of thousands of hospitalizations each year across the US. EV-D68 was first identified in California in the ...
FILE - This 2014 illustration made available by the U.S. Centers for Disease Control and Prevention depicts a polio virus particle. The polio virus has been found in New York City’s wastewater ...