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Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Coker v. Georgia, 433 U.S. 584 (1977) – The death penalty is unconstitutional for rape of an adult woman when the victim is not killed. Enmund v. Florida, 458 U.S. 782 (1982) – The death penalty is unconstitutional for a person who is a minor participant in a felony and does not kill, attempt to kill, or intend to kill. Tison v.
As of January 2024, there were nearly 2,200 prisoners facing the death penalty in state cases, according to the center, which states the death row population has been declining over the last 20 years.
It has also been suggested that mirtazapine has no significant serotonergic effects and is therefore not a dual action drug. [34] Bupropion has also been suggested to cause SS, [35] [36] although as there is no evidence that it has any significant serotonergic activity, it is thought unlikely to produce the syndrome. [37]
Three men still remain on federal death row after President Joe Biden issued sweeping commutations Monday to the sentences of 37 other prisoners who were awaiting execution.. Biden's decision is ...
Besides mirtazapine, they also block the α 1-adrenergic receptor [citation needed]. Conversely, whereas TCAs have relatively low affinity for the α 2 -adrenergic receptor , mianserin and mirtazapine potently antagonize this receptor, and this action is thought to be involved in their antidepressant effects [ citation needed ] .
The 2024 presidential election leaves people opposed to the death penalty in a quandary. The American people have returned to the White House someone who wants to expand the uses of capital ...