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Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.
In 44 of these cases the cause of death was natural causes or unclear. The remaining 115 deaths were due to accidents (N = 16), suicide (N = 60), drug addiction (N = 29) or alcoholism (N = 10). In a comparison of suicides and natural deaths, the concentrations both of flunitrazepam and nitrazepam (sleeping medications) were significantly higher ...
It has also been suggested that mirtazapine has no significant serotonergic effects and is therefore not a dual action drug. [34] Bupropion has also been suggested to cause SS, [35] [36] although as there is no evidence that it has any significant serotonergic activity, it is thought unlikely to produce the syndrome. [37]
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Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
With 15.5 million U.S. adults currently diagnosed with ADHD, there is a growing focus on warning signs of the disorder. Mental health experts share the most common signs and symptoms.
The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...
While most people think of a headache when they think about a migraine attack, the migraine is "actually affecting different brain processes, which are affecting the body," Dr. Susan Broner ...