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Keells Krest brand is one the 100 most valuable brands in Sri Lanka. The brand value of Keells Krest is estimated to be worth LKR1,127 million in 2022, a 12.6% growth from the previous year. [7] Keells Food Product is ranked 15th in LMD 100 second board in its 2020/21 edition. LMD 100 ranks publicly quoted companies of Sri Lanka by revenue ...
Keells is a Sri Lankan supermarket chain operated by Jaykay Marketing Services (Pvt) Ltd., a subsidiary of the John Keells Group. [1] Established in 1991, [1] [2] Keells has grown to operate 135 outlets across the country, positioning itself as one of the leading retail chains in Sri Lanka alongside other retailers such as Cargills, Glomark, Spar, and Arpico.
John Keells Logistics (Pvt) Ltd. is a logistic, supply chain management and transportation management company. It is a subsidiary of John Keells. It is a recipient of the ISO 9001:2015 and ISO 45001:2018 certifications. [9] Mackinnons is one of the oldest logistic companies in Sri Lanka. It was founded by India Steamship Company in 1917.
Bile salt diarrhea can also be a side-effect of gallbladder removal. [1] Bile acid sequestrants are the principal therapy for bile acid-induced diarrhea. [7] [1] Cholestyramine, colestipol and colesevelam have all been used. Doses may not need to be as high as those previously used for hyperlipidemia.
These conjugated bile acids are often referred to as bile salts. The pKa of the unconjugated bile acids are between 5 and 6.5, [ 4 ] and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water.
Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea.It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.
In the human liver, bile is composed of 97–98% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats (cholesterol, fatty acids, and lecithin), and 200 meq/L inorganic salts. [ 2 ] [ 3 ] The two main pigments of bile are bilirubin , which is orange-yellow, and its oxidised form biliverdin , which is green.
Bile salt hydrolases are members of the N-terminal nucleophilic hydrolase family, characterized by autocatalytic activation by an N-terminal nucleophile and subsequent amide bond cleavage. [ 2 ] [ 5 ] The majority of BSH enzymes are composed of homotetramers , although they have been known to assume other forms including homodimers and ...
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