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H4CBD (hydrogenated CBD, tetrahydrocannabidiol) is a cannabinoid that was first synthesized by Alexander R. Todd in 1940 derived from the catalytic hydrogenation of cannabidiol. [ 1 ] H2-CBD and 8,9-dihydrocannabidiol have also been referred to as "hydrogenated CBD", which may cause confusion.
Acute effects while under the influence can sometimes include euphoria or anxiety. [4] [5] Although some assert that cannabidiol (CBD), another cannabinoid found in cannabis in varying amounts, may alleviate the adverse effects of THC that some users experience, [6] little is known about CBD's effects on humans.
Studies examining this effect have used high ratios of CBD to THC, and it is unclear to what extent these laboratory studies translate to the types of cannabis used by real life users. [28] [40] Research has suggested that CBD can safely reduce some symptoms of psychosis in general. [41]
[4] [20] CBD does not have the same psychoactivity as THC, [25] [26] and can modulate the psychoactive effects of THC on the body if both are present. [17] [25] [27] [28] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC. [29]
Berberine can upset your gastrointestinal system, causing symptoms like: nausea, diarrhea, constipation, gas and abdominal pain, Simmons says. It’s also possible that taking berberine can ...
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People sometimes use cannabis to cope with their anxiety, and cannabis withdrawal can lead to symptoms of anxiety. [58] Buspirone , a serotonin 5-HT 1A receptor partial agonist , has shown limited efficacy for treating anxiety in people with cannabis use disorder, though there may be better efficacy in males than in females. [ 58 ]
Of course, if you're feeling sick, it’s a good idea to test yourself so you can know the full picture of what you’re dealing with, says Thomas Russo, MD, a professor and chief of infectious ...