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The Merck Manuals (outside the U.S. and Canada: The MSD Manuals; Chinese: 默沙东诊疗手册; pinyin: Mòshādōng Zhěnliáo Shǒucè) are medical references published by the American pharmaceutical company Merck & Co. (known as MSD outside the United States and Canada), that cover a wide range of medical topics, including disorders, tests, diagnoses, and drugs.
The first edition of The Merck Manual was published in 1899 by Merck & Co., Inc. for physicians and pharmacists and was titled Merck's Manual of the Materia Medica. [6] [7] The 192 page book which sold for US $1.00, was divided into three sections, Part I ("Materia Medica") was an alphabetical listing of all known compounds thought to be of therapeutic value with uses and doses; Part II ...
The symptoms of urethritis can include pain or a burning sensation upon urination (), a white/cloudy discharge and a feeling that one needs to pass urine frequently.For men, the signs and symptoms are discharge from the penis, burning or pain when urinating, itching, irritation, or tenderness.
Dysuria refers to painful or uncomfortable urination. [ 1 ] [ 2 ] It is one of a constellation of irritative bladder symptoms (also sometimes referred to as lower urinary tract symptoms), which includes nocturia and urinary frequency .
Frequent urination, or urinary frequency (sometimes called pollakiuria), is the need to urinate more often than usual. Diuretics are medications that increase urinary frequency.
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Benign prostatic hyperplasia (BPH); Bladder stone; Cancer of the bladder and prostate; Detrusor muscle weakness and/or instability; Diabetes; Use of ketamine [12]; Neurological conditions; for example multiple sclerosis, spinal cord injury, cauda equina syndrome
Signs indicative of urethral syndrome include a history of chronic recurrent urinary tract infections (UTI) in the absence of both conventional bacterial growth and pyuria (more than 5 white blood cells per high power field). [3]