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An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellular bacteria, protozoa, helminths, and fungi which could cause serious problems to the health of the host organism if not cleared from the body.
Processing of tumor antigens recognized by CD8+ T cells. Normal proteins in the body are not antigenic because of self-tolerance, a process in which self-reacting cytotoxic T lymphocytes (CTLs) and autoantibody-producing B lymphocytes are culled "centrally" in primary lymphatic tissue (BM) and "peripherally" in secondary lymphatic tissue (mostly thymus for T-cells and spleen/lymph nodes for B ...
Here, the immune system adapts its response during an infection to improve its recognition of the pathogen. This improved response is then retained after the pathogen has been eliminated, in the form of an immunological memory, and allows the adaptive immune system to mount faster and stronger attacks each time this pathogen is encountered. [4] [5]
It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell. [1] [2] In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their ...
In biology, it refers to damage caused to an organism by its own immune response, as a result of an infection. It could be due to mismatch between pathogen and host species, and often occurs when an animal pathogen infects a human (e.g. avian flu leads to a cytokine storm which contributes to the increased mortality rate).
Dendritic cells are named after their structure that resembles that of a dendrite of an axon, and they have two vital functions: display antigens, which are recognized by T cells and alert lymphocytes of the presence of an injury or infection. When the body is introduced to infection or injury, dendritic cells migrate to immune or lymphoid ...
The inflammatory response is characterized by the following symptoms: redness of the skin, due to locally increased blood circulation; heat, either increased local temperature, such as a warm feeling around a localized infection, or a systemic fever;
The term inflammation is not a synonym for infection. Infection describes the interaction between the action of microbial invasion and the reaction of the body's inflammatory response—the two components are considered together in discussion of infection, and the word is used to imply a microbial invasive cause for the observed inflammatory ...