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The insular cortex is divided by the central sulcus of the insula, into two parts: the anterior insula and the posterior insula in which more than a dozen field areas have been identified. The cortical area overlying the insula toward the lateral surface of the brain is the operculum (meaning lid ).
Normally, the insular opercula begin to develop between the 20th and the 22nd weeks of pregnancy. At weeks 14 to 16 of fetal development, the insula begins to invaginate from the surface of the immature cerebrum of the brain, until at full term, the opercula completely cover the insula. [4] This process is called opercularization. [5]
A literature review is an overview of previously published works on a particular topic. The term can refer to a full scholarly paper or a section of a scholarly work such as books or articles. Either way, a literature review provides the researcher/author
Agranular insula is a portion of the cerebral cortex defined on the basis of internal structure in the human, [1] the macaque, [2] the rat, [3] and the mouse. [4] Classified as allocortex (periallocortex), it is in primates distinguished from adjacent neocortex (proisocortex) by absence of the external granular layer (II) and of the internal granular layer (IV).
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The insula has been found to be activated by maternal and romantic love, as well as by pleasant and mesmerizing musical moments and deeper states of meditation. [1] [9] Besides the insula, the dopamine reward system of the ventral tegmental area and striatum or nucleus accumbens have also been found to be activated by musical moments. [1]