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2. Liver support system - Wikipedia

   en.wikipedia.org/wiki/Liver_support_system

   A liver support system or diachysis is a type of therapeutic device to assist in performing the functions of the liver. Such systems focus either on removing the accumulating toxins (liver dialysis), or providing additional replacement of the metabolic functions of the liver through the inclusion of hepatocytes to the device (bioartificial liver device).

3. Liver - Wikipedia

   en.wikipedia.org/wiki/Liver

   The liver is a major metabolic organ exclusively found in vertebrate animals, ... ammonia detoxification, and bile production and secretion. ...

4. Detoxification - Wikipedia

   en.wikipedia.org/wiki/Detoxification

   The liver and kidney are naturally capable of detox, as are intracellular (specifically, inner membrane of mitochondria or in the endoplasmic reticulum of cells) proteins such as CYP enzymes. In cases of kidney failure , the action of the kidneys is mimicked by dialysis ; kidney and liver transplants are also used for kidney and liver failure ...

5. Hepatocyte - Wikipedia

   en.wikipedia.org/wiki/Hepatocyte

   A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein synthesis; Protein storage; Transformation of carbohydrates; Synthesis of cholesterol, bile salts and phospholipids; Detoxification, modification, and excretion of exogenous and endogenous substances

6. Cirrhosis - Wikipedia

   en.wikipedia.org/wiki/Cirrhosis

   The liver plays a vital role in many metabolic processes in the body including protein synthesis, detoxification, nutrient storage (such as glycogen), platelet production and clearance of bilirubin. With progressive liver damage; hepatocyte death and replacement of functional liver tissue with fibrosis in cirrhosis, these processes are disrupted.

7. Glutamine synthetase - Wikipedia

   en.wikipedia.org/wiki/Glutamine_synthetase

   GS is present predominantly in the brain, kidneys, and liver. [4] [10] GS in the brain participates in the metabolic regulation of glutamate, the detoxification of brain ammonia, the assimilation of ammonia, recyclization of neurotransmitters, and termination of neurotransmitter signals. [4] [14] GS, in the brain, is found primarily in ...