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4-Chloroaniline is used in the industrial production of pesticides, drugs, and dyestuffs. It is a precursor to the widely used antimicrobial and bacteriocide chlorhexidine and is used in the manufacture of pesticides, including pyraclostrobin , anilofos , monolinuron , and chlorphthalim .
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4-Chloro-o-toluidine (4-COT, 4-chloro-2-methylaniline) is the organic compound with the formula CH 3 C 6 H 3 Cl(NH 2). It is a colorless solid. The compound is produced as an intermediate to the pesticide chlordimeform and a precursor to some azo dyes. Production has declined after it was shown to be highly carcinogenic.
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The industry-sponsored Insecticide Resistance Action Committee (IRAC) advises on the use of insecticides in crop protection and classifies the available compounds according to their chemical structures and mechanism of action so as to manage the risks of pesticide resistance developing. [4] The 2024 IRAC poster of insecticide modes of action ...
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