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Anaphylaxis is a severe allergic reaction of rapid onset affecting many body systems. [ 5 ] [ 8 ] It is due to the release of inflammatory mediators and cytokines from mast cells and basophils , typically due to an immunologic reaction but sometimes non-immunologic mechanism.
Also, shellfish allergy is the most common cause of anaphylaxis in adults and adolescents particularly in East Asian countries like Hong Kong, Taiwan, Singapore, and Thailand. [93] Individuals in East Asia have further developed an allergy to rice , which forms a large part of their diet. [ 98 ]
Shellfish allergies are highly cross reactive, but its prevalence is much higher than that of fish allergy. Shellfish allergy is the leading cause of food allergy in U.S adults. [31] As of 2018 six allergens have been identified to prawn alone; along with crab, it is the major culprit of seafood anaphylaxis. [13]
About 220 cases of anaphylaxis and 3 deaths per year are due to latex allergy. [150] An estimated 150 people die annually from anaphylaxis due to food allergy. [151] Between 1999 and 2006, 48 deaths occurred in people ranging from five months to 85 years old. Insect venom: Around 15% of adults have mild, localized allergic reactions.
Mast cell activation syndrome (MCAS) is a term referring to one of two types of mast cell activation disorder (MCAD); the other type is idiopathic MCAD. [1] MCAS is an immunological condition in which mast cells, a type of white blood cell, inappropriately and excessively release chemical mediators, such as histamine, resulting in a range of chronic symptoms, sometimes including anaphylaxis or ...
Today, 6 million American children live with food allergies, and young Asian Americans like Wong’s son, now in college, are 40% more likely to develop one compared to the general population.
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The human immune system is designed to protect the body from potential harm and in people who have allergies the immune system will react to allergens (substances that trigger an immune response). The immune system will produce immunoglobulin E, IgE, antibodies for each allergen. The antibodies will cause cells in the body to produce histamine ...