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Many clinical trials have been recently completed or are ongoing for new therapies for Crohn's disease. They include the following: They include the following: Certolizumab is a PEGylated Fab fragment of a humanized anti-TNFα monoclonal antibody that was found to have efficacy over placebo in one large trial.
Vedolizumab eventually completed a number of phase III clinical trials [24] [25] for Crohn's Disease and Ulcerative Colitis (GEMINI I, [26] GEMINI II, [27] and GEMINI III [28]) that demonstrate that vedolizumab is an effective and well tolerated drug.
The Crohn's & Colitis Foundation (The Foundation) is a volunteer fueled non-profit organization in the US that works to fund research to find cures for Crohn's disease and ulcerative colitis, collectively known as inflammatory bowel disease (IBD), and to improve the quality of life of children and adults affected by these digestive diseases.
The Crohn's Disease Activity Index (CDAI) is a scoring system to assess the symptoms associated with Crohn's disease. It assigns a score based on eight clinical factors, including overall well-being, frequency of loose stools, abdominal pain, presence of abdominal masses, changes in weight, low hemoglobin levels, and use of opiates for diarrhea.
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
The trial was to have started July 15. ... There's no known cure for Crohn's disease, but therapies can greatly reduce its signs and symptoms and even bring about long-term remission and healing ...
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