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Dr. Mandel: Ketamine Infusion Therapy is typically prescribed for a series of six intravenous (IV) infusions of ketamine, for 50 to 55 minutes, over the course of two to three weeks. The amount is ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
Dr. Brandon Hamm, a psychiatrist who runs the ketamine infusion clinic at Northwestern Medicine in Chicago, said that the drug’s value lies, in part, in how fast it works.
Ketamine is a rapid-acting antidepressant, [19] but its effect is transient. [58] Intravenous ketamine infusion in treatment-resistant depression may result in improved mood within 4 hours reaching the peak at 24 hours.
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
Ketamine can be concerning if it’s mixed with other drugs, Alan says. “When ketamine is mixed with things like alcohol and opioids, it can make the effects of these drugs greater,” she says.
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Ketamine is suitable for hypotensive patients, or patients with risks of developing hypotension (e.g. those who have hypovolemia, hemorrhage, sepsis or severe cardiovascular compromise). [ 40 ] [ 41 ] This is because ketamine is associated with increased blood pressure, heart rate and cardiac output. [ 42 ]