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Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen.
An allergen is an otherwise harmless substance that triggers an allergic reaction in sensitive individuals by stimulating an immune response.. In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. [1]
Other food allergies, affecting less than 1 person per 10,000 population, may be considered "rare". [46] The most common food allergy in the US population is a sensitivity to crustacea. [46] Although peanut allergies are notorious for their severity, peanut allergies are not the most common food allergy in adults or children. Severe or life ...
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In higher organisms, an allergic response may be the cause of irritation. An allergen is defined distinctly from an irritant, however, as allergy requires a specific interaction with the immune system and is thus dependent on the (possibly unique) sensitivity of the organism involved while an irritant, classically, acts in a non-specific manner.
Wheat allergy symptoms should not be confused with celiac disease, gluten ataxia or non-celiac gluten sensitivity (NCGS). While wheat allergies are "true" allergies, celiac disease and gluten ataxia are an autoimmune diseases. [62] NCGS is more similar to food intolerances but as of 2021 its pathogenesis is still not well understood.
Red, itchy, or watery eyes are common symptoms of seasonal allergies, but they're also signs of pink eye, or conjunctivitis. Here’s how to tell the difference.
Salicylate sensitivity is a pharmacological reaction, not a true IgE-mediated allergy. However, it is possible for aspirin to trigger non-allergic hypersensitivity reactions. [8] [9] About 5–10% of asthmatics have aspirin hypersensitivity, but dietary salicylates have been shown not to contribute to this.