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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity.
Obesity isn’t just a matter of food and exercise — it may be in your genetic code, according to new research. “Obesity’s causes are very complex and in the majority of cases, the ...
Genetics. Certain genetic conditions can also cause obesity. For example, Prader-Willi syndrome is an inherited disorder that leads to, among other complications, intellectual disability, a short ...
Depending on the degree of obesity and the presence of comorbid disorders, obesity is associated with an estimated 2–20 year shorter life expectancy. [37] [36] High BMI is a marker of risk for, but not a direct cause of, diseases caused by diet and physical activity. [13]
Monogenic obesity is excess weight caused by a mutation in a single gene, as opposed to syndromic obesity not tied to a single gene variation and most obesity, which is caused by multiple genetic and environmental risk factors. Monogenetic obesity mostly affects the hypothalamus and leptin–melanocortin system (see hypothalamic obesity ...
“Obesity is a multifactorial disease, and genetics is just one component. The researchers emphasized that even people with ‘skinny genes’ still must eat the right foods and exercise.”
Steatopygia, a genetic characteristic leading to increased accumulation of adipose tissue in the buttock region, is most notably (but not solely) found among the Khoisan of Southern Africa. It has also been observed among Pygmies of Central Africa and also the Andamanese people, such as the Onge tribe in the Andaman Islands. This genetic ...
Pathophysiology of obesity is the study of disordered physiological processes that cause, result from, or are otherwise associated with obesity. A number of possible pathophysiological mechanisms have been identified which may contribute in the development and maintenance of obesity.