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XCircuit is a schematic capture program for drawing publication-quality VLSI electrical circuit schematic diagrams and related figures. It's part of the Open Circuit Design tools. It's primarily intended for ULSI/VLSI IC design and not for PCB design, the latter though is still possible. [2]
Gene Designer is a computer software package for bioinformatics. [ 1 ] [ 2 ] It is used by molecular biologists from academia, government, and the pharmaceutical, chemical, agricultural, and biotechnology industries to design, [ 3 ] clone, and validate genetic sequences.
The phosphorylation of Rb by CDK4/6 and CDK2 dissociates the Rb-repressor complex and serves as an on/off switch for the cell cycle. Once Rb is phosphorylated, the inhibition is released on the E2F transcriptional activity. This allows for the transcription of S phase genes encoding for proteins that amplify the G1 to S phase switch.
Genetic regulatory circuits (also referred to as transcriptional regulatory circuits) is a concept that evolved from the Operon Model discovered by François Jacob and Jacques Monod. [ 1 ] [ 2 ] [ 3 ] They are functional clusters of genes that impact each other's expression through inducible transcription factors and cis-regulatory elements .
Cis-regulatory elements (CREs) or cis-regulatory modules (CRMs) are regions of non-coding DNA which regulate the transcription of neighboring genes.CREs are vital components of genetic regulatory networks, which in turn control morphogenesis, the development of anatomy, and other aspects of embryonic development, studied in evolutionary developmental biology.
At the moment, circuit design is improving at a slow pace because of insufficient organization of known multiple gene interactions and mathematical models. This issue is being addressed by applying computer-aided design (CAD) software to provide multimedia representations of circuits through images, text and programming language applied to ...
A computational gene [1] [2] [3] is a molecular automaton consisting of a structural part and a functional part; and its design is such that it might work in a cellular environment. The structural part is a naturally occurring gene , which is used as a skeleton to encode the input and the transitions of the automaton (Fig. 1A).
List of free analog and digital electronic circuit simulators, available for Windows, macOS, Linux, and comparing against UC Berkeley SPICE. The following table is split into two groups based on whether it has a graphical visual interface or not.