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The endogenous orexin neuropeptides, orexin A and orexin B, are involved in the regulation of sleep–wake cycles and act to promote wakefulness. [33] [16] [7] Deficiency of orexin signaling is thought to be the primary cause of the sleep disorder narcolepsy. [33] [16] Disturbances in orexin signaling may also be involved in insomnia. [33]
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...
Darby Dan Farm is a produce, livestock, and thoroughbred horse breeding and training farm founded in 1935 near the Darby Creek in Galloway, Ohio by businessman John W. Galbreath. [1] Named for the creek and for Galbreath's son, Daniel M. Galbreath (1928–1995), it was expanded from an original 85-acre (340,000 m 2 ) farm into a 4,000 acre (16 ...
Aerial view of the facility in 1994. Beulah Park opened in Grove City, Ohio, a suburb of Columbus, in 1923.It was the first thoroughbred racetrack in Ohio.At its close it was one of only three tracks in Ohio to offer live thoroughbred racing, the others being Thistledown in North Randall and River Downs in Cincinnati.
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Horses on the Pryor Mountains Wild Horse Range in Montana. The BLM distinguishes between "herd areas" (HA) where feral horse and burro herds existed at the time of the passage of the Wild and Free-Roaming Horses and Burros Act of 1971, and "Herd Management Areas" (HMA) where the land is currently managed for the benefit of horses and burros, though "as a component" of public lands, part of ...
Horses in hard training may need a vitamin E supplement, as their requirements are higher than horses in more moderate work. The horse may also be deficient in selenium, and need a feed in supplement. Selenium can be dangerous if overfed, so a blood test to confirm that the horse is in need of supplemental selenium should be used. [1]
In 2007, the U.S. Government Accountability Office published an examination of the deaths of several teens attending programs in which endurance tests were part of their treatment. In testimony before Congress, GAO officials quoted from one program brochure, which advertised that the first five days were “days and nights of physical and ...
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