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The first four seem to be involved in the hydroxylation of toluene to benzyl alcohol. CYP2E1 seems to be the primary enzyme in the hydroxylation of toluene, accounting for roughly 44% of toluene metabolism; [1] however, there is a great deal of ethnic variability, in the Finnish population for example the primary enzyme is CYP2B6.
Toluene is also found in cigarette smoke and car exhaust. If not in contact with air, toluene can remain unchanged in soil or water for a long time. [39] Toluene is a common solvent, e.g. for paints, paint thinners, silicone sealants, [40] many chemical reactants, rubber, printing ink, adhesives (glues), lacquers, leather tanners, and ...
Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...
A documentary by Karen Davila showed the effects of inhalant abuse on a person's body. [1] The chemical toluene provides the aromatic smell of contact cement and other glue and is the culprit behind the addiction. Toluene abusers are exposed to levels above 1000 ppm (parts per million). Levels of exposure greater than 600 ppm cause confusion ...
Toluene (or methylbenzene) is a common chemical found in chemistry laboratories. An alkylbenzene is a chemical compound that contains a monocyclic aromatic ring attaching to one or more saturated hydrocarbon chains. [ 1 ]
Toxic leukoencephalopathy may also result from carbon monoxide poisoning, ingestion of methanol, ingestion of ethylene, [8] toluene toxicity, [3] ethanol poisoning, ingestion of methylenedioxymethamphetamine (MDMA or "ecstasy"), or ingestion of paradichlorobenzene, [18] which is a toxic agent in mothballs.
Cannabis sativa, also known to the Romans as Cannabion, asterion, and Schoinostrophon, was mentioned numerous times in Roman medical literature. [7] [8] Roman doctors such as Dioscorides and Galen wrote that cannabis could be used to create strong ropes, repel mosquitos, and that it would decrease sexual activity, cause impotence, and cause nausea.
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