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  2. Grapefruit–drug interactions - Wikipedia

    en.wikipedia.org/wiki/Grapefruit–drug_interactions

    Analgesic and behavioral effects were reported for 12 hours and plasma samples were analyzed for oxycodone metabolites for 48 hours. Grapefruit juice increased the mean area under the oxycodone concentration-time curve (AUC(0-∞)) by 1.7 fold, the peak plasma concentration by 1.5-fold and the half-life of oxycodone by 1.2-fold as compared to ...

  3. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/lifestyle/grapefruit-interfere...

    A single glass of grapefruit juice can interfere with your body's ability to break down a medication. ... "Many food-drug interactions and potential side effects can be avoided by following ...

  4. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...

  5. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

    www.aol.com/diabetes-drugs-really-safe-reliable...

    Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed. That said, no medication is without side effects.

  6. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin is more commonly associated with gastrointestinal adverse effects than most other antidiabetic medications. [46] [77] The most serious potential adverse effect of metformin is lactic acidosis; this complication is rare, and seems to be related to impaired liver or kidney function.

  7. Grapefruit can interfere with your medications — here's what ...

    www.aol.com/grapefruit-interfere-medications...

    A single glass of grapefruit juice can interfere with your body's ability to break down a medication. Here's how to protect your health.

  8. Why Doctors Are Calling This Common Medication a ... - AOL

    www.aol.com/why-doctors-calling-common...

    Metformin is a safe, effective and cheap, and is showing it has promise for longevity, long Covid, weight control and other issues. ... “As long as you have good renal function, the side effects ...

  9. Canagliflozin/metformin - Wikipedia

    en.wikipedia.org/wiki/Canagliflozin/metformin

    The most common side effects include hypoglycemia (low blood glucose levels) when used in combination with insulin or a sulphonylurea and vulvovaginal candidiasis (thrush, a fungal infection of the female genital area caused by Candida).

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