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Sodium butyrate is a compound with formula Na(C 3 H 7 COO). It is the sodium salt of butyric acid . It has various effects on cultured mammalian cells including inhibition of proliferation , induction of differentiation and induction or repression of gene expression. [ 1 ]
Recreational doses of 1–2 g generally provide a feeling of euphoria, and larger doses create deleterious effects such as reduced motor function and drowsiness. [9] The sodium salt of GHB has a salty taste. [31] Other salt forms such as calcium GHB and magnesium GHB have also been reported, [34] but the sodium salt is by far the most common.
Butyrate is also reduced in a diet low in dietary fiber, which can induce inflammation and have other adverse affects insofar as these short-chain fatty acids activate PPAR-γ. [50] Butyrate exerts a key role for the maintenance of immune homeostasis both locally (in the gut) and systemically (via circulating butyrate).
There can be side effects from supplementation, such as bad-smelling breath and sweat and headaches, as well as digestive issues such as heartburn, nausea or diarrhea, Harvard’s site stated.
Traveller's diarrhea's symptoms treated with an enema of sodium butyrate, organic acids, and A-300 silicon dioxide can be successfully decreased with lack of observed side effects. [ 7 ] Shigellosis treatment benefits from adjunct therapy with butyrate enemas, promoting healing of the rectal mucosa and inflammation, but not helping in clinical ...
The US label for sodium oxybate has a black box warning because it is a central nervous system depressant (CNS depressant) and for its potential for abuse.Other potential adverse side effects include respiratory depression, seizures, coma, and death, especially when it is taken in combination with other CNS depressants such as alcohol.
Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.
Sodium phenylbutyrate, sold under the brand name Buphenyl among others, is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. [7] The compound is used to treat urea cycle disorders , because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen.
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