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The technetium-99m radioisotope is used predominantly in bone and brain scans. For bone scans , the pertechnetate ion is used directly, as it is taken up by osteoblasts attempting to heal a skeletal injury, or (in some cases) as a reaction of these cells to a tumor (either primary or metastatic) in the bone.
The metastable technetium-99m (99m Tc) is a short-lived (half-life about 6 hours) nuclear isomer used in nuclear medicine, produced from molybdenum-99. It decays by isomeric transition to technetium-99, a desirable characteristic, since the very long half-life and type of decay of technetium-99 imposes little further radiation burden on the body.
The pertechnetate ion (/ p ər ˈ t ɛ k n ə t eɪ t /) [1] is an oxyanion with the chemical formula TcO − 4 . It is often used as a convenient water-soluble source of isotopes of the radioactive element technetium (Tc).
Sodium pertechnetate is the inorganic compound with the formula NaTcO 4. This colourless salt contains the pertechnetate anion, TcO − 4 that has slightly distorted tetrahedron symmetry both at 296 K and at 100 K [ 2 ] while the coordination polyhedron of the sodium cation is different from typical for scheelite structure.
A renogram, which may also be known as a MAG3 scan, allows a nuclear medicine physician or a radiologist to visualize the kidneys and learn more about how they are functioning. [1] MAG3 is an acronym for mercapto acetyl tri glycine , a compound that is chelated with a radioactive element – technetium-99m .
A technetium-99m pertechnetate scan, also called Meckel scan or nuclear scintigraphy scan, is the investigation of choice to diagnose Meckel's diverticula in children. This scan detects gastric mucosa ; since approximately 50% of symptomatic Meckel's diverticula have ectopic gastric or pancreatic cells contained within them, [ 24 ] this is ...
The MUGA scan is performed by labeling the patient's red blood pool with a radioactive tracer, technetium-99m-pertechnetate (Tc-99m), and measuring radioactivity over the anterior chest as the radioactive blood flows through the large vessels and the heart chambers. [citation needed]
The agent of choice for this purpose is technetium-99m pertechnetate. [17] Initially it provides a radionuclide angiogram, followed by a static image after the radionuclide has perfused the tissue. In the healthy patient, initial images show symmetric flow to the testes, and delayed images show uniformly symmetric activity. [17]